Observe that this list is just not all-inclusive and features only widespread medications that will interact with oxycodone. You ought to refer to the prescribing details for oxycodone for a complete listing of interactions.

Tell your Health care company when you reside inside a household the place you can find smaller children or somebody who has abused street or prescription medicine, having prescription or above-the-counter medicines, vitamins, or herbal health supplements. Having OxyContin with particular other medicines might cause major side effects that could result in death.

In addition, discontinuation of the concomitantly applied cytochrome P450 3A4 inducer may well bring about an increase in oxycodone plasma focus. Often Consider people receiving oxycodone and any CYP3A4 inhibitor or inducer 

Retail store at space temperature, far from heat, humidity, and light-weight. Keep an eye on your drugs. Oxycodone is actually a drug of abuse and you should be mindful if any person is using your medication improperly or without a prescription.

Observational research have shown that concomitant utilization of opioid analgesics and benzodiazepines improves the possibility of drug-associated mortality when compared with usage of opioid analgesics alone. As a result of similar pharmacological Attributes, it's affordable to expect related possibility Together with the concomitant use of other CNS depressant drugs with opioid analgesics [see Drug Interactions (seven)].

Alternate analgesics may be required if individual isn't a applicant for most affordable offered dose power.

Dose conversions really should be done carefully and with shut monitoring on account of substantial individual variability in opioid analgesic response; it is actually preferable to underestimate a individual's 24-hour oral oxycodone need and supply rescue medication than to overestimate and manage an adverse response.

Because elderly people are more likely to have diminished renal operate, care ought to be taken in dose variety, and it might be practical to watch renal purpose.

Choose with plenty of h2o to ensure finish swallowing; never pre-soak, lick or otherwise soaked just before swallowing.

Go over The provision of naloxone for your unexpected emergency procedure of opioid overdose Using the affected individual and caregiver and assess the potential need for use of naloxone, both of those when initiating and renewing treatment with oxycodone HCl tablets [see Warnings and Safeguards (5.3), Client Counseling Facts (seventeen)]. click here Advise sufferers and caregivers about the varied strategies to acquire naloxone as permitted by personal condition naloxone dispensing and prescribing prerequisites or pointers (e.

Totally free and conjugated noroxycodone, no cost and conjugated oxycodone, and oxymorphone are excreted in human urine subsequent only one oral dose of oxycodone. The foremost circulating metabolite is noroxycodone with an AUC ratio of 0.six relative to that of oxycodone. Oxymorphone is current within the plasma only in small concentrations. The analgesic exercise profile of other metabolites is just not acknowledged at present.

Oxycodone is a complete opioid agonist and is fairly selective for that mu-opioid receptor, although it can bind to other opioid receptors at bigger doses. The principal therapeutic motion of oxycodone is analgesia.

Oxycodone hydrochloride (HCl) tablets are indicated for that administration of discomfort significant more than enough to need an opioid analgesic and for which choice therapies are insufficient.

Oxycodone HCl tablets USP, fifteen mg are supplied as green, spherical, biconvex tablets debossed with "A" to the remaining and "forty nine" on the correct with the score on one particular side and simple on another facet.